Leading 14-0 at the break (Keaton Ackerman had gone two-for-two on extra points), the Lakers extended that margin on its first possession of the third quarter. Hopsicker went 17 yards and, when Camden tried to stop him, Vogl broke free for a 23-yard gain.
Hopsicker finished it off with an eight-yard TD run, which made it 20-0,and the first of Hopsicker's interceptions led to Vogl breaking loose for his longest run of the night, a 58-yard dash to the end zone that accounted for more than a quarter of his eventual 222 yards on the ground, done on 28 carries.
Jeremy Zeitschel did score from nine yards out to get Camden on the board late in the third quarter, but that proved the exception. Twice more, the Lakers ended drives with fourth-down stops, and two other times Hopsicker stepped into errant passes.
Early in the fourth quarter, from Camden's 31, the Lakers feinted a pass outside, but Hopsicker instead went over the top - and found Seeley in mid-stride for the game's final touchdown.
Cazenovia has its home opener at Buckley-Volo Field next Saturday at 1:30 against the Class B East division's newest member - Central Valley Academy. The combined Ilion and Mohawk squads, nicknamed the Thunder, are also 1-0 following a 30-9 win over Mexico in its first-ever varsity contest.