Nolan would add a goal in the second half and McGuane would score three times as Hunt and Burrows matched Nolan with two goals apiece, but Skaneateles never let the Mustangs get closer the rest of the way.
Powers, with four goals and two assists, led the attack, while Beatson, Navaroli, Molly Wood and Casey VanSlyke each scored twice and Logan would tack on a second-half goal.
And so the Mustangs moved on, hoping that it would get a third chance in the post-season to take Skaneateles down, and met General Brown Saturday afternoon, looking far from sharp but still registering a 12-8 victory over the Lions.
During an active first half, Marcellus steadily built a 9-4 lead, which proved important since General Brown slowed the game down in the second half, making small inroads but not catching up.
Nolan finished with five goals and one assist, while Audrey Cerrone found the net three times. Hunt had a goal and three assists as McGuane, Ally Burrows and Lexy Bird had one goal apiece.
At 12-2, Marcellus still had one more home game on Monday, against Westhill, preceding a Wednesday trip to Chittenango and the start of the Section III Class C playoffs this weekend.